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Polymeric nanoparticles (e.g., PLGA) can improve solubility and exposure with strong regulatory precedent, but degradation-driven release may be less programmable for multi-trigger redox logic ( A pragmatic decision rule is as follows: choose MSNs when the primary requirement is architectural control over interfacial redox kinetics (stability + conditional release) and when a safety/reproducibility package can be credibly assembled

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Results from natural remedies like vitamin C or turmeric can take several weeks to appear

2008;(2):CD003917