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Norepinephrine transporter in major depressive disorder: a PET study

Adapted with permission from Stapled helical peptides bearing different anchoring residues, by Li X, Chen S, Zhang WD, Hu HG

Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]

OxLDL also plays a pro-inflammatory role by stimulating endothelial cells to express adhesion molecules, such as vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) [71]