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The Pei 2024 meta-analysis has a larger total patient pool (1,458 vs 472), giving it more overall statistical power

Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S (2009) Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Implementing cycles (e.g., 5 days on, 2 days off, or several weeks on followed by a break) allows the body's natural systems to recalibrate

You wonder if the very thing meant to help you perform better is actually slowing you down