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Am J Obstetrics Gynecol (1993) 169(6):15459

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Accelerated approval for Filspari was granted based on data from the Phase III PROTECT study, which showed that the small molecule blocker lowered urine protein levels more than three times as much as the active control, Avapro

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importantly, suppressing this axis reduced metastatic fitness, supporting FSP1 as a context-selective vulnerability in melanoma progression 117

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