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The acute aldehyde storm increases hepatic GSH consumption in the Aldh2*2 KI mice with decreased aldehyde detoxification, resulting in increased hepatic ferroptosis To investigate the cause of the systemic and hepatic aldehyde accumulation in the Aldh2*2 KI homozygous mice, we investigated hepatic expression of aldehyde detoxification enzymes

Inoculation and yeast propagation were performed in a medium containing potato wastewater enriched with glycerol (Avantor Performance Materials, Poland) in an amount of 5% (w/v)

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