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All of these cases involved smokers, and the histopathological specimens exhibited airway-centered cystic lesions with fibrosis, accompanied by bronchiolar metaplasia, mucostasis, and fibroblastic foci (Figs

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Likewise, both e-cigarette aerosol and CS extract increased cell death in adenocarcinomic human alveolar basal epithelial cells (A549 cells), and again the effect was more damaging with CS extract than with e-cigarette aerosol (detrimental effects found at 2 mg/mL of CS extract vs

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