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POM is rich in polyphenolic antioxidants, which include tannins, ellagic acid, gallic acid, and others.[ , , , ] Pomegranate and ellagic acid antioxidant properties have been proven on many occasions

In addition, specific amino acid deficiency or the immunosuppressive effect of certain amino acid metabolism can damage the function of immune cells, including effector T cells, in the tumor microenvironment

Oxidative stress occurs when there is an imbalance between the production of cell-damaging free radicals and the body's ability to neutralize them, a state that is heavily implicated in the pathophysiology of complex chronic illnesses

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