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162 A systematic literature review concluded that vigorous aerobic exercise and resistance training can lower male hormone levels and improve insulin sensitivity, while a randomized controlled trial in 61 women with PCOS found that a program of yoga exercise also may be of benefit as it reduced unwanted hair growth, abdominal circumference, and hip circumference compared with controls

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As expected, the overexpression of PCBP1 and PCBP2 significantly inhibited the ability of ACE to increase lipid peroxidation and Fe 2+ , which further confirmed our speculation (Fig