de la Torre BG, Albericio F (2023) The pharmaceutical industry in 2022: an analysis of FDA drug approvals from the perspective of molecules
Unlike oral supplements, which may cause gastrointestinal side effects and take weeks to show results, IV iron infusion delivers iron directly into the bloodstream, allowing for faster absorption and quicker improvement in iron levels
Glutathiones main roles include: Neutralizing harmful free radicals Acting as a cofactor for several antioxidant enzymes Regenerating vitamins C and E Neutralizing free radicals produced by Phase I liver metabolism of chemical toxins, including formaldehyde, acetaminophen, benzpyrene, and many other compounds Participating in Phase I and Phase II detoxification reactions Adhering to toxins and heavy metals (including mercury) before carrying them out of the body Regulating cellular proliferation and apoptosis Participating in mitochondrial function and the maintenance of mitochondrial DNA Essentially, glutathione is crucial for shielding cells from endogenous and exogenous reactive oxygen and nitrogen species, as well as dealing directly with the causes of oxidative stress such as mercury and pollutants
Our findings raise the notion that reductions in key antioxidant mechanisms may be the biological risk factor for the development of konzo, particularly those mediated through pathways involving the glutathione peroxidase family
