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Safety outcomes assessed included baseline and peak activated partial thromboplastin time, incidence of epistaxis, blood-tinged sputum, pulmonary bleeding, gastrointestinal hemorrhage, major bleeding, heparin-induced thrombocytopenia, anaphylaxis, bronchospasm, and respiratory deterioration during or immediately after administration of inhaled nebulised HABIT or any other adverse events

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Because both delta sleep and GH secretion peak concurrently in the early night, DSIP's sleep-deepening effects and GH-modulating effects may represent two manifestations of the same underlying neuroendocrine circuit restoration