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Progress is hindered by the confounding effects of host genetics, diet, and environment, the heterogeneity of microbial sampling and sequencing methodologies, and the limited fidelity of rodent models in recapitulating human smoking behaviors

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The stated key indication to treat problems of the mind, together with the effects described by our informant as opening of the psychic-mental, suggest parallels to psychedelic-assisted therapies, a rapidly growing trend in current psychiatry research (Tupper et al., 2015