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Berberine may be a valuable potential therapeutic target for various neurodegenerative diseases, as data based on both in vitro models and animal models of neurodegenerative diseases support the beneficial effects of berberine

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Possibly, the consistent endothelium protection during advanced healing processes in different wounds of various tissues, including blood vessels [1,2,1017], associated with the counteraction of the L-NAME-induced disturbances as well as the counteraction of the L-arginine-induced disturbances, obtained with the same BPC 157 dose range [14,15,1826], should likely compete with the prominent endothelium effect of the heparin-impaired endothelial nitric oxide (NO) synthesis [36] as well as warfarin endothelium damage [37]