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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease

Methylcobalamin, a form of vitamin B12, is utilized in the treatment of various conditions such as neuropathy, anemia, B12 deficiency, megaloblastic anemia, and Leber's disease

CAS 137525-51-0 Molecular formula CHNO Molecular weight 1419.53 g/mol Sequence GEPPPGKPADDAGLV Soluble in water (1 mg/mL) and standard aqueous buffers

The fact that high levels of GST are associated with resistance to apoptosis induced by a range of substances, including chemotherapeutic agents, supports its putative role in MAPK signaling prevention