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3.4 Osteoporosis Osteoporosis is typified by excessive bone resorption that arises via hyperactive osteoclasts, and is highly regulated by the RANKL/RANK signalling axisits activation initiates subsequent signalling of NF-B and MAPK to promote osteoclast differentiation and bone loss (Table 1, Row 19)

Accordingly, maintenance of a healthy mitochondrial network, defined as mitochondrial homeostasis, is critical for normal mitochondrial function during development and even throughout life

Formation of a GS-conjugate is also part of the camalexin biosynthetic pathway (Bttcher et al., 2009)

The copper part is essential to the molecules function, as it carries copper and hands it off where cells can use it