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This approach has been described as a senolytic strategy selectively eliminating senescent cells while sparing non-senescent cells that do not depend on the FOXO4-p53 interaction for survival

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J.SurewiczK.NadaudP

The hippocampus shows reduced functional connectivity bilaterally to widespread regions, including the fusiform gyrus, frontal gyrus, temporal gyrus, anterior and posterior cingulate gyri, medial frontal gyrus, precuneus, and inferior parietal lobule, compared to healthy controls [105]