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In reviewing this issue, it is unclear why the requestor did not include branch retinal artery occlusion (BRAO) in their request for FY 2024 rulemaking

NF-kB is activated by canonical and non-canonical signalling pathways which has different signalling compounds and its biological functions

ORCID: Affiliation: 6 Instituto de Farmacologia e Neurocincias, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal 7 Centro Cardiovascular da Universidade de Lisboa, CCUL (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal These authors contributed equally to this work

Thus, there is a need for specific treatment options that rapidly eliminate these pathogenic IgG auto-Abs