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APC emphasizes the need for more comprehensive information about the FDA's substance-specific safety concerns

It is a known fact that eNOS-derived NO is essential in angiogenesis by enhancing vascular endothelial growth factors and up-regulating the recruitment of endothelial progenitor cells from the bone marrow [142, 143]

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Studies and case reports have revealed that NET formation may increase dramatically in COVID-19 infections, suggesting that neutrophils and NETs play a substantial role in immunity against SARS-CoV-2 [28, 29]