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Differential effects of reduced mineralocorticoid receptor activation by unilateral adrenalectomy vs mineralocorticoid antagonist treatment in patients with primary aldosteronism - implications for depression and anxiety

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Out of 75 cases, 56 were women (74.7%) and 19 were men (25.3%), supporting the known female predominance in autoimmune diseases

For instance, glomerular filtration rate, as an index of kidney damage, must be reduced to about 50% before plasma urea and creatinine concentration rise above the upper limit of their respective reference range (George and Neilson, 2015)