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(3) basolateral extrusion of Ca 2+ via plasma membrane Ca 2+ -ATPase PMCA1b and (4) Ca 2+ extrusion into the blood (15, 16)

In DSS-induced mouse models, oral administration of periodontitis-derived salivary microbiota (PSM) exacerbated anxiety-like behaviors, altered gut microbiota composition, reduced cortical neuron counts, and activated microglia

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The lack of success in neuroprotective R&D in the 1990s and 2000s generated a lot of skepticism for developing brain injury therapeutics, Korinek acknowledges