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This relationship is also evident at a genetic level, as the deletion of fatty acid desaturase 1/2 (FADS1/2) genes in mice showed BD-like behavior with both hypo and hyperactive episodes, which responded to lithium [159]

Blood sugar fluctuations, insulin resistance, and mitochondrial strain increase: Oxidative stress Pro-inflammatory cytokine signaling Nervous system reactivity Impaired cellular recovery Even subtle metabolic instability can make pain more persistent and resistant to conventional treatment

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Some countries have banned this product because of a potential connection to the development of cancer