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This, in part, reflects the challenge and mistrust of the medical establishment, which worsened during the Covid pandemic, but was already showing strong signs of opposition by the wide adoption of supplements (with a very similar lack of supportive data on efficacy and safety) long before 2020

investigated for selective fat-mobilising effects independent of GH receptor signalling Cartilage & joint research Examined in chondrocyte models and osteoarthritis frameworks for anabolic effects on cartilage matrix synthesis Metabolic profile Investigated for absence of the hyperglycaemic and IGF-1-elevating effects associated with full-length hGH, making it a useful tool compound for isolating GHs metabolic effects Body composition models Studied in rodent obesity models for changes in fat mass, lean mass, and energy expenditure Clinical research history Progressed to early-phase human trials in Australia (2000s) for obesity and osteoarthritis indications

UK patients should consult their GP and report any suspected adverse effects to the MHRA via the Yellow Card Scheme